Research ethics across the 49th parallel: the potential value of pilot testing "equivalent protections" in Canadian research institutions.

摘要: Abstract Canada and the United States share world's largest trade partnership an increasing concern about divergent regulatory approaches to common industries. Canadian research institutes receive more funding from U.S. National Institutes of Health than any other country, much it fund multi-centre collaborative between two countries. Because these close economic ties, extensive similarities countries in review oversight ethics human subjects research, we propose that would be ideal country for a pilot-test feasibility "equivalent protections", regulation permits comparison protections institutions The protections" has been advocated by various bodies as potentially beneficial mechanism improving foreign trials. As well, argue could prove valuable five specific ways: (1) reducing administrative burden on administering federal funding; (2) creating symbolic value explicit recognition procedures normally followed protection are at least equivalent those provided regulations; (3) lowering opportunity cost investing Canada; (4) affording enhance its leadership role international offering alternative model subjects; (5) providing how idea might addressed funded agencies but conducted ********** Introduction Geographically, longest undefended border, majority which straddles 49th parallel. partnership, amounting approximately $650 billion dollars per year goods services This is often characterized one-directional flow exports States, since 85% U.S., whereas 25% good Canada, 2003 Canada's imports exceeded all 25 European Union. have long respected tradition bilateral arrangements scientific exchange, industrial national security environment, say nothing recognizable commonalities culture, sports, entertainment. Recently, light increasingly well recognized interdependence our status there some quiet calls improved harmonization vast regulating industries Currently 300 treaties agreements force provide frameworks partnerships range enterprises. Although precise seldom considered difficult quantify, health with clearly important strategic priority both governments, considerable impact Collectively 2003, received almost $50 million (U.S.) Heath (NIH), $200 awarded institutions. Much this supports involving subjects, so common, or comparable, standards readily apparent. …