Management of digestive tract fistulas. A review.

作者: M. Falconi , N. Sartori , E. Caldiron , R. Salvia , C. Bassi

DOI: 10.1159/000051489

关键词:

摘要: Digestive tract fistulas are a complex subject in terms both of classification and management. There is still lack firm epidemiological data regarding the their incidence, though prognostic factors conditioning prognosis these patients now well known. They related mainly to nutritional status presence or otherwise sepsis. Instrumental investigations should be aimed not merely at identifying complication, but also guiding clinicians choice therapeutic According various situations arising, treatment will surgical, endoscopic conservative medical. In latter case, clinician establish first all whether, as result site fistula status, patient requires total parenteral enteral artificial nutrition, whenever possible. those cases which nutrition indicated, ideal drug with best proven ability shorten healing times reduce number complications when used combination naturally occurring somatostatin dose 250 micrograms/h over 24 h. other cases, if clinically important, its synthetic analogue, octreotide, can administered subcutaneously. The amount octreotide ranges from 300 600 micrograms/day 3 4 daily doses.

参考文章(29)
S. Finnegan, N. A. Scott, M. H. Irving, Octreotide and postoperative enterocutaneous fistulae: a controlled prospective study. Acta Gastro-enterologica Belgica. ,vol. 56, pp. 266- 270 ,(1993)
M. Falconi, F. Nifosi, D. Lombardi, C. Bassi, R. Girelli, Pitfalls of Medical Treatment Springer Berlin Heidelberg. pp. 162- 166 ,(1992) , 10.1007/978-3-642-77418-8_15
John L. Rambeau, Rolando H. Rolandelli, Enteral and parenteral nutrition in patients with enteric fistulas and short bowel syndrome. Surgical Clinics of North America. ,vol. 67, pp. 551- 571 ,(1987) , 10.1016/S0039-6109(16)44232-5
F. Nifosi, M. Falconi, E. Montresor, S. Vesentini, Limitations of Conservative Therapy of Pancreatic Fistulas Springer Berlin Heidelberg. pp. 155- 161 ,(1992) , 10.1007/978-3-642-77418-8_14
Zahid A. Saeed, Francisco C. Ramirez, Kenneth S. Hepps, Endoscopic stent placement for internal and external pancreatic fistulas Gastroenterology. ,vol. 105, pp. 1213- 1217 ,(1993) , 10.1016/0016-5085(93)90970-N
J. J. Sancho, J. Di Costanzo, P. Nubiola, A. Larrad, A. Beguiristain, F. Roqueta, G. Franch, A. Oliva, J. M. Gubern, A. Sitges-Serra, Randomized double-blind placebo-controlled trial of early octreotide in patients with postoperative enterocutaneous fistula. British Journal of Surgery. ,vol. 82, pp. 638- 641 ,(2005) , 10.1002/BJS.1800820521
L. F. Hollender, C. Meyer, D. Avet, B. Zeyer, Postoperative fistulas of the small intestine: therapeutic principles. World Journal of Surgery. ,vol. 7, pp. 474- 480 ,(1983) , 10.1007/BF01655936
Moshe Schein, George A.G. Decker, Postoperative external alimentary tract fistulas. American Journal of Surgery. ,vol. 161, pp. 435- 438 ,(1991) , 10.1016/0002-9610(91)91107-T
Markus Büchler, Helmut Friess, Istvan Klempa, Peter Hermanek, Udo Sulkowski, Heinz Becker, Anton Schafmayer, Ivo Baca, Dietmar Lorenz, Richard Meister, Bernd Kremer, Peter Wagner, Jens Witte, Ernst Ludwig Zurmayer, Hans-Detlev Saeger, Bernd Rieck, Peter Dollinger, Karl Glaser, Reinhard Teichmann, Jochen Konradt, Wilhelm Gaus, Hans-Joachim Dennler, Dieter Welzel, Hans G. Beger, Role of octreotide in the prevention of postoperative complications following pancreatic resection. American Journal of Surgery. ,vol. 163, pp. 125- 131 ,(1992) , 10.1016/0002-9610(92)90264-R
A. Sitges-Serra, E. Jaurrieta, A. Sitges-Creus, Management of postoperative enterocutaneous fistulas: The roles of parenteral nutrition and surgery British Journal of Surgery. ,vol. 69, pp. 147- 150 ,(2005) , 10.1002/BJS.1800690310