Does minimal access major surgery in the newborn hurt less? An evaluation of cumulative opioid doses.

摘要: Abstract Background Minimal access surgery (MAS) in adults is associated with less postoperative pain comparison to conventional ‘open’ surgery. It not known whether this holds true for neonates as well. Less would imply that opioid consumption can be reduced, which has a beneficial effect on morbidity. Aim To evaluate potential differences in’ between undergoing thoracoscopic minimal or of esophageal atresia (EA) and congenital diaphragmatic hernia (CDH). Methods In retrospective cohort study we included two controls each MAS patient, matched diagnosis, sex age at Opioid dose titration was based validated scores (VAS COMFORT behaviour), applied by protocol. Cumulative doses 12, 24, 48 h 7 days postoperatively were compared groups the Mann–Whitney test. Results The group consisted 24 patients (14 EA; 10 CDH). These 48 control (28 20 At none time points cumulative (median mg/kg (IQR)) significantly differed controls, both CDH EA. For example 24 h [0.84(0.61–1.83) vs. 1.06(0.60–1.36) p = 1.0] EA [0.48(0.30–0.75) 0.49(0.35–0.79) p = 0.83] controls. This held Conclusions repair doses.