New silyl-functionalized BisGMA provides autonomous strengthening without leaching for dental adhesives.
作者： Linyong Song , Qiang Ye , Xueping Ge , Anil Misra , Candan Tamerler
DOI: 10.1016/J.ACTBIO.2018.10.033
关键词:
摘要: Abstract Resin-based composite has overtaken dental amalgam as the most popular material for direct restorative dentistry. In spite of this popularity clinical lifetime restorations is threatened by recurrent decay. Degradation adhesive leads to gaps at composite/tooth interface–bacteria, bacterial by-products and fluids infiltrate leading decay restoration failure. The durability resin-dentin bonds a major problem. We address problem synthesizing silyl-functionalized BisGMA (e.g., silyl-BisGMA), formulating adhesives with new monomer determining physicochemical properties leaching characteristics silyl-BisGMA adhesives. Silyl-BisGMA was synthesized stoichiometric amounts 3-isocyanatopropyl trimethoxysilane (IPTMS). control mixture based on HEMA/BisGMA (45/55, w/w). experimental formulations, partially or completely replaced silyl-BisGMA. Water miscibility, polymerization behavior (Fourier transform infrared spectroscopy, FTIR), thermal property (modulated differential scanning calorimetry, MDSC), mechanical in dry wet conditions (dynamic analysis, DMA), leached species (HPLC) were investigated. Data from all tests submitted appropriate statistical analysis (α = 0.05). Silyl-BisGMA-containing exhibited comparable water lower viscosities, significantly improved degree conversion C bond compared control. After 4 weeks aqueous aging, glass transition temperature rubbery moduli copolymers greater than (p Statement Significance low-viscosity that tooth (enamel dentin) intended seal stabilize interface, but it degrades breach margin. As crosslinking adhesives, Bisphenol A-glycerolate dimethacrylate (BisGMA) limitations, e.g. susceptible hydrolysis concomitant degradation. A methoxysilyl-functionalized derivative (silyl-BisGMA) introduced work respond these limitations. Our results indicated introducing silyl-BisGMA, higher crosslinked networks obtained without sacrificing homogeneity, amount HEMA reduced up 99%. This novel resin offers potential benefits including prolonging functional materials.
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