Alteration by Kainate of Energy Stores and Neuronal-Glial Metabolism of Glutamate In Vitro
作者： William J. Nicklas
DOI: 10.1007/978-1-4757-0384-9_5
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摘要: Kainate was found to decrease the energy charge of cerebellar slices and increase inosine monophosphate levels. In addition, it caused leakage glutamate aspartate from tissue decreased synthesis glutamine a variety radioactive precursors. These effects were attributed alterations in glial cells secondary massive depolarization neurons. results those others are discussed terms their implication for mechanism neurotoxicity excitatory substances.
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