Human cortical regions activated by wide-field visual motion: an H2(15)O PET study.

摘要: 1. Several areas in the monkey dorsal visual pathway, including part of medial superior temporal area, have been found to contain cells responding movements a wide field and are suggested be involved analyzing self-induced motion information. In present study, positron emission tomography was used localize human cortical regions wide-field motion. Changes regional cerebral blood flow (rCBF) were measured when subjects maintained fixation viewed low-contrast (0.15 log units brighter than background) dots subtending 80 x degrees moving either coherently or incoherently. Brain foci localized after activity fixation-only paradigm subtracted from that two dot paradigms. 2. Both coherent incoherent significantly activated primary/secondary cortex surrounding cuneus occipital gyrus. Subtraction images between showed caused by types movement comparable these early regions. 3. lateral occipitotemporoparietal cortex, specifically separate areas; posterior focus located at border right occipitotemporal gyri, dorsoanterior bilaterally temporoparietal cortex. The did not activate 4. A fine anatomic localization using individual magnetic resonance performed for bilateral activation which mainly depth inferior parietal lobule small portion middle gyri. 5. within intraparietal sulcus (Brodmann area 7). more anteriorly movement. movements, however, reveal any significant rCBF increases lobule. 6. other known visuospatial visuomotor functions also movement, frontal eye 8) premotor 6) lobe. 7. posteriorly occipito-temporal gyri corresponds homologue reported previous studies medium-sized stimuli. appeared rely on stimulation.