Misdiagnosis of cystic fibrosis — Experience from Germany
作者： Lutz Naehrlich , Azadeh Bagheri-Behrouzi
DOI: 10.1016/J.JCF.2012.06.008
关键词:
摘要: Abstract Background Misdiagnosis of cystic fibrosis (CF) is rare. We investigated patients with misdiagnoses CF in Germany, and compared diagnosed before after 1990. Methods analysed data from the German quality assurance project rechecked CF-centre directors. Results Between 1989 2004, diagnoses were withdrawn 51 5.79years (median), whose diagnosis was based on nonspecific symptoms between 1979 2001 at median age 4.33years. transmembrane conductance regulator (CFTR) dysfunction indicated by unreliable sweat tests (45.1%), pathologic chloride (37.3%), genetic (3.9%), nasal potential difference measurements (13.1%). Patients 1990 older (6.13 vs 1.21years), more frequently fulfilled diagnostic criteria (77.4% 20%) experienced respiratory (83.9% 50%). Conclusions To detect CF, CF-centres should re-evaluate atypical courses new or transferred patients.
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