Carbon Nanotube Based Sensor for Simultaneous Determination of Acetaminophen and Ascorbic Acid Exploiting Multiple Response Optimization and Measures in the Presence of Surfactant
作者： Eduardo Henrique Duarte , Lauro Tatsuo Kubota , César Ricardo Teixeira Tarley
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摘要: A simple procedure for the simultaneous determination of acetaminophen (AC) and ascorbic acid (AA) by differential pulse voltammetry (DPV) using a carbon nanotube paste electrode exploiting measures in cetylpyridinium bromide (CPB) medium is described. Under best instrumental parameters DPV, optimized means factorial design, calibration plots range 100.0–700.0 µmol L−1 (r=0.993) 39.4–146.3 µmol L−1 (r=0.995) with limits detection 7.1 2.1 µmol L−1, were achieved AA AC, respectively. The developed method was successfully applied AC pharmaceutical formulations, whose accuracy attested comparison HPLC method.
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