Mood changes in adolescents using depot-medroxyprogesterone acetate for contraception: a prospective study.

摘要: Abstract Study Objective: Depot-medroxyprogesterone acetate (DMPA) is thought to cause changes in mood among patients using it for contraception. The purpose of this study was evaluate negative and positive affect adolescent females DMPA as a contraceptive agent. Design, Setting, Participants: This prospective set an urban hospital clinic. Thirty-nine adolescents choosing agent 24 not any hormonal contraception were enrolled subjects controls, respectively. Two standardized questionnaires, the Beck Depression Inventory (BDI) Multiple Affect Adjective Checklist–Revised (MAACL-R), administered at baseline all participants readministered 3, 6, 12 months. Main Outcome Measures: Changes from months evaluated by BDI “dysphoria” subscale scores MAACL-R. Paired t -tests used measure these controls separately. Results: mean change one year those who completed −4.8 ( P = .02) +.3 .84) controls. dysphoria −5.7 .21) −.1 .98) while over period −2.1 .46) +.1 Conclusions: Adolescents do show depressive symptoms when measured no significant or