RNA matchmaking in chromatin regulation.

摘要: Beyond being the product of gene expression, RNA can also influence regulation chromatin. The majority human genome has capacity to be transcribed and non-protein-coding transcripts made by Polymerase II are enriched in nucleus. Many chromatin regulators bind these ncRNAs nucleus; some cases, there clear examples direct RNA-mediated mechanisms stemming from interactions, while others have yet determined. Recent studies highlighted via matchmaking, a term we use broadly here describe intermolecular base-pairing interactions between one molecule an or DNA match. This review provides matchmaking that regulates processes summarizes technical approaches used capture events.