Identification of human parvovirus B19 infection in idiopathic nonimmune hydrops fetalis
作者： Jeanne A. Jordan
DOI: 10.1016/S0002-9378(96)70370-8
关键词:
摘要: Abstract OBJECTIVE: This retrospective study was designed to determine the incidence of B19 associated with idiopathic nonimmune hydrops fetalis by use a sensitive molecular tool, polymerase chain reaction assay. STUDY DESIGN: Placental and fetal tissues from 57 cases were analyzed for deoxyribonucleic acid. Thirty-four these classified as idiopathic. The remaining 23 had known, noninfectious-based causes. RESULTS: Eighteen percent all (6/34) contained In contrast, none examined any Presence virus confirmed in each six either B19-specific acid situ hybridization or immunocytochemistry. However, histologic examination unsuccessful at detecting characteristic viral-like inclusions one third cases. CONCLUSION: significant finding demonstrates usefulness aid differential diagnosis this disease. (AM J OBSTET GYNECOL 1996;174:37-42.)
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