How does bovine serum albumin prevent the formation of kidney stone? A kinetics study.

作者: Junfeng Liu , Huaidong Jiang , Xiang-Yang Liu

DOI: 10.1021/JP057403B

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摘要: To attain a better understanding of the crystallization calcium oxalate crystals under influence protein bovine serum albumin, we examined not only nucleation kinetics but also structural synergy between biomineral and biosubstrate. It follows that during process albumin inhibits by increasing kink barrier. The results scanning electron microscopy X-ray diffraction show, however, promotes formation dihydrate. Apart from this, facilitates ordered crystal assembly suppressing supersaturation-driven interfacial structure mismatch. physics questions behind mentioned effects have been addressed point view. This may explain why plays an important role in urine stone formation.

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