Is the frequency of self-monitoring of blood glucose related to long-term metabolic control? Multicenter analysis including 24,500 patients from 191 centers in Germany and Austria.

摘要: Blood glucose measurements are generally accepted components of a modern diabetes self-management. The value self-monitoring blood (SMBG) is, however, discussed controversially and only few studies addressed the efficacy SMBG under real-life conditions so far. In order to investigate whether frequency is related long-term metabolic control, data from DPV-Wiss-database, standardized,prospective, computer-based documentation care outcome, were analyzed for patients with type 1(n = 19,491) 2 (n 5,009) 191 centers in Germany Austria. Local HbA1c reference ranges mathematically adjusted DCCT reference. For each patient, most recent year used. On average,patients 1 performed 4.4 measurements/day. Corrected age, gender, duration,on intensified (>or=4 daily injections or CSII) therapy (HbA1c reduction 0.32% one additional SMBG/day) compared on conventional (1-3 injections) therapy(HbA1c-reduction 0.16% SMBG/day). 2,021 insulin-treated (2.7 measurements/day), more frequent was associated better control (HbA1c-reduction additionalSMBG/day, p or= 4 < 0.0001), while 2,988 OAD diet alone (2.0 higher HbA1c-levels(HbA1c-increase 0.14% SMBG/day, 0.0001). These indicate that both, diabetes. Since no benefit found alone, should primarily be recommended those suboptimal whereas SHBG non-insulin-treated adequate HbA1c-levels remains uncertain.