Early urinary angiotensinogen excretion in critically ill neonates.
作者： Qing Wang , Mengxia Li , Xiaozhong Li , Jian Pan , Jian Wang
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摘要: Introduction: Urinary angiotensinogen is considered a reliable biomarker for intrarenal renin-angiotensin system activity. The aims of this study were to assess the urinary level during first day life and evaluate its correlation with renal function in critically ill neonates. Methods: concentration 24 hours was measured 98 Neonatal assessed by levels cystatin-C, albumin α1-microglobulin electrolyte excretion. Results: decreased increasing gestational age body weight neonates (P<0.001). After adjustment age, correlated fractional excretion sodium cystatin-C α1-microglobulin. Multivariate linear regression identified significant impact on Furthermore, significantly increased cystatin-C-to-creatinine ratio ⩾2500 ng/mg, which optimal cut-off value predict acute kidney injury our previous study. Conclusions: correlates overall maturity early postnatal period an might reflect immature
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