Short term low-calorie diet improves insulin sensitivity and metabolic parameters in obese women

作者: Grazielle Vilas Bôas Huguenin , Sofia Kimi Uehara , José Firmino Nogueira Netto , Egberto Gaspar de Moura , Glorimar Rosa

DOI: 10.3305/NH.2014.30.1.7464

关键词:

摘要: Obesity and insulin resistance are associated with an increase of cardiovascular risk factors, including adipocytokines. The aim this study was to investigate the effect low-calorie diet on serum lipids, adipokines, body composition in obese women. It a clinical trial class I women aged 30-45 years submitted hypocaloric for 90 days. Dietary intake, anthropometric parameters, composition, glucose, insulin, leptin, adiponectin, HOMA-IR QUICKI indexes were evaluated at baseline, 30, 60 There 30% significant decrease energy also weight, mass index waist circumference (p < 0.01) throughout treatment period. Despite amount lean (kg) reduced average, it observed that (%) had increased fat decreased significantly third month 0.05). Systolic blood pressure up -5mmHg 0.05) after Was until 60th day, while adiponectin during treatment. Corroborating reduction leptin 0.01). These results suggest short-term reduces total fat, mainly found abdominal region, efficiently improve sensitivity decreasing

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