1,2,4-Triazolines

摘要: Publisher Summary The formation of a 1,2, 4-triazoline heterocycle was first observed by Pinner, in the course his classic work on synthesis amidrazones reaction an imidate with hydrazine; 15 years later, example synthesized Busch and Ruppenthal cyclocondensation amidrazone aldehyde. Since then, birth concept 1,3-dipolar cycloadditions along discovery several new classes 1,3-dipoles from laboratories Huisgen associates has contributed greatly to development 1,2,4-triazoline chemistry. This chapter surveys synthesis, physical properties, chemical reactions 1,2,4-triazolines covers literature through 1986 middle 1987. Triazolines bearing ring-linked functions that are potentially aromatic, such as 4, =S, =N-R, =CRR not considered.