Nasal delivery of cyclodextrin complexes of anti-inflammatory steroids
作者： Ranga R. Namburi , Burgise F. Palkhiwala , Sucharitha Jagini
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摘要: Aqueous, anti-inflammatory steroid compositions in solution form suitable for nasal administration and having a reduced stinging sensation are provided as well method treating inflammation of the mucosa by intranasal compositions. These may result enhanced bio-availability. The composition includes an amount from about 0.0001 % to 2.0 (w/v); cyclodextrin 0.1 20 alcohol co-solvent .2 35% crystallization inhibitor where required, effective antimicrobial preservative; antioxidant; chelating agent; water; pH adjusting agent sufficient adjust 4 7.
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