Targeted delivery to beta cells
作者： Amit Choudhary , Debasish MANNA , LEE Miseon , Bridget Wagner
DOI:
关键词:
摘要: The disclosure includes zinc prodrugs for targeted delivery of therapeutic, diagnostic or imaging agents to β-cells and methods use therefor. also small molecules that stabilize activate CRISPR effector proteins comprising at least one destabilization domain, enable CRISPR-based genome editing transcriptional activation repression in β-cells.
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