VARIATIONS IN MATERNAL PLASMA LEVELS OF HUMAN PLACENTAL LACTOGEN (HPL) IN NORMAL PREGNANCY AND LABOUR

作者: Bo S. Lindberg , Bo A. Nilsson

DOI: 10.1111/J.1471-0528.1973.TB16037.X

关键词:

摘要: Summary Plasma levels of human placental lactogen (HPL) in normal pregnancy from the 22nd week until delivery were measured with a rapid radioimmunoassay. The HPL concentration plasma rose steadily up to 37th and thereafter gradually decreased delivery. Individual women followed during latter part showed characteristic pattern very small deviations their original relative level within range. Significant fluctuations noted 24-hour period sampling shorter periods. No systematic circadian variation was observed. variations no clear relation sleep, meals or light exercise. During spontaneous induced labour significant concentrations occurred but these same magnitude as those pregnancy; correlation between uterine contraction relaxation found. Strenuous physical exercise last month sufficient affect fetal heart rate did not influence levels.

参考文章(15)
B. Lindberg, B. A. Nilsson, A. Roth, L. Ylänen, Estimation of Human Chorionic Somatomammotropin (HCS) Levels during Normal Pregnancy Using a Rapid Radioimmunoassay Upsala Journal of Medical Sciences. ,vol. 77, pp. 129- 132 ,(1972) , 10.1517/03009734000000018
Daniel W. Cramer, Paul Beck, Edgar L. Makowski, Correlation of gestational age with maternal human chorionic somatomammotropin and maternal and fetal growth hormone plasma concentrations during labor American Journal of Obstetrics and Gynecology. ,vol. 109, pp. 649- 655 ,(1971) , 10.1016/0002-9378(71)90641-7
J.E. Tyson, G.S. Jones, J. Huth, P. Thomas, Patterns of insulin, growth hormone, and placental lactogen release after protein and glucose-protein ingestion in pregnancy American Journal of Obstetrics and Gynecology. ,vol. 110, pp. 934- 942 ,(1971) , 10.1016/0002-9378(71)90547-3
William N. Spellacy, Karen L. Carlson, Sharon A. Birk, Dynamics of human placental lactogen. American Journal of Obstetrics and Gynecology. ,vol. 96, pp. 1164- 1173 ,(1966) , 10.1016/0002-9378(66)90529-1
M. HARTOG, HUMAN CHORIONIC SOMATOMAMOTRAOPHIN AND ITS CLINICAL SIGNIFICANCE Clinical Endocrinology. ,vol. 1, pp. 209- 218 ,(1972) , 10.1111/J.1365-2265.1972.TB00392.X
A. T. Letchworth, R. J. Boardman, Christine Bristow, J. Landon, T. Chard, A RAPID SEMI-AUTOMATED METHOD FOR THE MEASUREMENT OF HUMAN CHORTONIC SOMATOMAMMOTROPHIN. THE NORMAL RANGE IN THE THIRD TRIMESTER AND ITS RELATION TO FETAL WEIGHT BJOG: An International Journal of Obstetrics and Gynaecology. ,vol. 78, pp. 542- 548 ,(1971) , 10.1111/J.1471-0528.1971.TB00313.X
Melvin M. Grumbach, Selna L. Kaplan, J. J. Sciarra, Ian M. Burr, CHORIONIC GROWTH HORMONE-PROLACTIN (CGP): SECRETION, DISPOSITION, BIOLOGIC ACTIVITY IN MAN, AND POSTULATED FUNCTION AS THE “GROWTH HORMONE” OF THE SECOND HALF OF PREGNANCY* Annals of the New York Academy of Sciences. ,vol. 148, pp. 501- 531 ,(1968) , 10.1111/J.1749-6632.1968.TB20372.X