Toxicity of concurrent stereotactic radiotherapy and targeted therapy or immunotherapy: A systematic review

作者: Stephanie G.C. Kroeze , Corinna Fritz , Morten Hoyer , Simon S. Lo , Umberto Ricardi

DOI: 10.1016/J.CTRV.2016.11.013

关键词:

摘要: Background and purpose Both stereotactic radiotherapy (SRT) and immune-or targeted therapy play an increasingly important role in personalized treatment of metastatic disease. Concurrent application of both therapies is rapidly expanding in daily clinical practice. In this systematic review we summarize severe toxicity observed after concurrent treatment. Material and methods PubMed and EMBASE databases were searched for English literature published up to April 2016 using keywords “radiosurgery”,“local ablative therapy”,“gamma …

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