Medical Therapy of Hepatocellular Carcinoma

摘要: The principles underlying medical management of hepatocellular carcinoma (HCC) are based on an understanding the clinical setting, tumor characteristics, and biology. Reviewing our patient population, we found that 81% had cirrhosis 19% no evidence by biopsy or computed tomography (CT) scan (Table 1). male/female ratio was 2.5:1, 72% patients were caucasian. Interestingly, 24% symptoms at all but diagnosed either finding elevated liver function test results routine physical examination as incidental finding, such a work-up for some unrelated disease. A further 17% because planned surveillance CT screening known history hepatitis B C, cirrhosis, both. Eighteen percent which include ankle swelling, abdominal bloating, increased girth, pruritus, encephalopathy, gastrointestinal (GI) bleed, full 40% pain presentation. This seemed to be most common presenting symptom in population. We also significant proportion experienced weight loss, general malaise weakness, loss appetite. recently (unpublished data) more than 80% report sexual desire within proceeding 12 months diagnosis. seems sensitive nonspecific correlate cancer analysis systematic study quality-of-life questionnaires. characteristics tend display interesting patterns. In experience, HCC is typically multifocal bilobar 1, characteristics), thus not surgeon’s addition, portal vein invasion main branch vein, judged occlusion flow expansion scan, occurred 75% 2).