A Practical Primer on Prion Pathology.

摘要: Prion diseases comprise a group of transmissible degenerative encephalopathies resulting from propagation misfolded cellular protein uncertain function. As is generally the case with rare diseases, lack institutional experience compromises individual familiarity varying, and apparently protean, manifestations prion both clinically pathologically. Coupled documented transmissibility these within between species, Centers for Disease Control Prevention (CDC) has established National Pathology Surveillance Center to aid diagnosis disease survey United States evidence zoonotic transmission. We have assembled this primer hope that our accumulated will enable neuropathological community help CDC "save lives protect people."