APTR is a prognostic marker in cirrhotic patients with portal hypertension during TIPS procedure.
作者： Shanshan Yu , Yanhua Qi , Jue Jiang , Hua Wang , Qi Zhou
DOI: 10.1016/J.GENE.2017.12.040
关键词:
摘要: Portal hypertension is a major cause of mortality and morbidity in cirrhotic patients. In this study, we aimed to analyze the clinical characteristics Alu-mediated p21 transcriptional regulator (APTR) during transjugular intrahepatic portosystemic shunt (TIPS) procedure. hepatic venous blood was drawn from 84 patients with liver cirrhosis portal before after TIPS treatment. Then, detected biochemical, hemodynamic parameters APTR expression Indeed, treatment could markedly ameliorate serum urea nitrogen (BUN) level vein hemodynamics We found that levels significantly decreased its aberrant were positively correlated Model for End Stage Liver Disease (MELD), pressure gradient (PHPG) Higher associated poor prognosis. an independent predictors mortality. Our data indicated may serve as novel biomarker receiving TIPS.
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