Molecular properties of GABAergic local-circuit neurons in the mammalian visual cortex.

摘要: Publisher Summary It is likely that morphological and functional features unique to a particular subpopulation of gamma-aminobutyric acid–releasing (GABAergic) neurons are mediated by molecules the identification these will ultimately provide mechanistic basis for features. This chapter provides evidence justify this view. In many areas mammalian cortex, including visual have been characterized extensively Golgi method. About seven distinct types local circuit classified based on axonal arborizations dendritic patterns. Many now known accumulate [ 3 H]GABA, or their terminals can be labeled immunocytochemically GABA synthesizing enzyme, glutamic acid decarboxylase (GAD), indicating they GABAergic inhibitory neurons. The specific generally names given reflect branching Reagents, such as lectins antibodies, valuable tool in definition subpopulations cortex.