A novel method to synthesize (L)-β-hydroxyl esters by the reduction with bakers' yeast

作者: Kaoru Nakamura , Yasushi Kawai , Atsuyoshi Ohno

DOI: 10.1016/S0040-4039(00)94389-2

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摘要: Abstract β-Keto esters are reduced stereoselectively into the corresponding (L)-β-hydroxyl in presence of ethyl chloroacetate.

参考文章(8)
Kaoru Nakamura, Yasushi Kawai, Shinzaburo Oka, Atsuyoshi Ohno, Stereochemical Control in Microbial Reduction. 8. Stereochemical Control in Microbial Reduction of β-Keto Esters Bulletin of the Chemical Society of Japan. ,vol. 62, pp. 875- 879 ,(1989) , 10.1246/BCSJ.62.875
Kaoru Nakamura, Masato Higaki, Kazutoshi Ushio, Shinzaburo Oka, Atsuyoshi Ohno, Stereochemical control of microbial reduction. 2. Reduction of β-keto esters by immobilized bakers' yeast Tetrahedron Letters. ,vol. 26, pp. 4213- 4216 ,(1985) , 10.1016/S0040-4039(00)98995-0
Woanru Shieh, Aravamudan S. Gopalan, Charles J. Sih, Stereochemical control of yeast reductions. 5. Characterization of the oxidoreductases involved in the reduction of .beta.-keto esters Journal of the American Chemical Society. ,vol. 107, pp. 2993- 2994 ,(1985) , 10.1021/JA00296A038
Kaoru Nakamura, Yasushi Kawai, Shinzaburo Oka, Atsuyoshi Ohno, A new method for stereochemical control of microbial reduction. Reduction of β-keto esters with bakers' yeast immobilized by magnesium alginate Tetrahedron Letters. ,vol. 30, pp. 2245- 2246 ,(1989) , 10.1016/S0040-4039(00)99659-X
Charles J. Sih, Ching-Shih Chen, Microbial Asymmetric Catalysis?Enantioselective Reduction of Ketones [New Synthetic Methods (45)] Angewandte Chemie International Edition in English. ,vol. 23, pp. 570- 578 ,(1984) , 10.1002/ANIE.198405701
Kaoru Nakamura, Kiyoko Inoue, Kazutoshi Ushio, Shinzaburo Oka, Atsuyoshi Ohno, Effect of Allyl Alcohol on Reduction of β-Keto Esters by Bakers’ Yeast Chemistry Letters. ,vol. 16, pp. 679- 682 ,(1987) , 10.1246/CL.1987.679
Jack Hine, Cyrus H. Thomas, Stanton J. Ehrenson, The Effect of Halogen Atoms on the Reactivity of Other Halogen Atoms in the Same Molecule. V. The SN2 Reactivity of Methylene Halides1 Journal of the American Chemical Society. ,vol. 77, pp. 3886- 3889 ,(1955) , 10.1021/JA01619A061