Endothelial markers in malignant vascular tumours of the liver: superiority of QB-END/10 over von Willebrand factor and Ulex europaeus agglutinin 1.

作者: P P Anthony , P Ramani

DOI: 10.1136/JCP.44.1.29

关键词:

摘要: A new monoclonal antibody, QB-END/10, raised against the CD34 antigen in human endothelial cell membranes and haemopoietic progenitor cells, was studied for its usefulness as a marker of neoplastic vascular cells 21 angiosarcomas seven malignant haemangioendotheliomas liver. QB-END/10 both more sensitive specific than Von Willebrand factor (VWF) Ulex europaeus 1 agglutinin (UEA-1) labelling it did not cross react with epithelia UEA-1 often does. Staining uniformly strong clear all histological variants these two tumours. should prove particularly useful differential diagnosis tumours

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