N-3 Fatty Acids for Hypertriglyceridemia in Patients Taking Second-Generation Antipsychotics
作者： Jeffrey Charles Fetter , Mary Brunette , Alan I. Green
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摘要: Objective: Cardiovascular disease is a frequent cause of early disability and death in patients with severe mental illness (SMI). Second-generation antipsychotic medications may increased risk cardiovascular some by elevating serum triglyceride levels. Idiopathic hypertriglyceridemia can be effectively treated N-3 fatty acid (N-3 FA) supplementation, but little research has evaluated this treatment for that occur using second-generation antipsychotics. Methods: A six-week, open-label pilot study FA, two grams twice daily, was performed to assess efficacy supplement SMI who were being Serum levels (the main endpoint) assessed at baseline six weeks. Levels C-reactive protein (CRP), cholesterol (total, high density lipoprotein [HDL] low [LDL]), fasting glucose, insulin (to calculate the Homeostatic Mo...
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