High educational performance is a distinctive feature of bipolar disorder: a study on cognition in bipolar disorder, schizophrenia patients, relatives and controls

摘要: Background Schizophrenia is associated with lower intelligence and poor educational performance relative to the general population. This is, a lesser degree, also found in first-degree relatives of schizophrenia patients. It unclear whether bipolar disorder I (BD-I) patients their have similar intellectual as that observed schizophrenia. Method cross-sectional study investigated two outpatient samples [494 BD-I patients, 952 spectrum (SCZ) patients], 2231 SCZ 1104 healthy controls 100 control siblings. Mixed-effects regression models were used compare groups on performance. Results more likely completed highest level education (odds ratio 1.88, 95% confidence interval 1.66-2.70) despite having IQ compared (β = -9.09, s.e. 1.27, p <0.001). In contrast, showed both -15.31, 0.86, <0.001) levels controls. Siblings patient had significantly than siblings, but did not differ scores between parents parents, higher levels. Conclusions Although controls, they education. contrasts who deficits Since demonstrate superior performance, our data suggest high may be distinctive feature