作者: Ann M. Ryan , Ernest Borek
DOI: 10.1016/S0079-6603(08)60328-1
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摘要: Publisher Summary This chapter reviews the variety of possible mechanisms for relaxed control phenomenon, without expressing prejudices toward any them. It that a single genetic locus in RNA synthesis as “RC” and considered its effectiveness to be “relaxed” all derivatives original mutant regardless amino acid deficiency imposed. While species accumulated RC mutants, excess DNA seemed relatively minor during an absolute starvation. discusses concept well. Since significant this macromolecule is observed only when gradual depletion supply occurs, it our view magnitude reflects adequacy starvation rather than genetically controlled relaxation. Synthesis completion replication cycle acid-starved strains exhibit stringent over also discussed. New insights new skills are needed field solicitation these goal chapter. hoped auxotrophs mammalian cells have become reality, question existence similar phenomenon may open exploration.