노루궁뎅이버섯 균사체로 발효한 민들레잎 추출물의 항염증 활성

摘要: This study investigated the fermentation effect of Taraxacum platycarpum Dahlst. leaf extracts using Hericium ernaceum mycelia to test antioxidant and anti-inflammatory activities in vitro. The fermented or non-fermented T. leaves were determined by 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity, ferric reducing power, 2,2"-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) activity. extract showed higher activity than leaves. However, ethanolic decreased levels nitric oxide production pro-inflammatory cytokines such as interleukin-6 tumor necrosis factor-α lipopolysaccharide-stimulated RAW 264.7 cells. Moreover, suppressed protein expression inducible synthase cell culture. Therefore, enhanced might be attributed molecular conversion ingredients during active have specific affinity with ethanol extraction.