Sensational placodes: neurogenesis in the otic and olfactory systems.

摘要: For both the intricate morphogenetic layout of sensory cells in ear and elegantly radial arrangement neurons nose, numerous signaling molecules genetic determinants are required concert to generate these specialized neuronal populations that help connect us our environment. In this review, we outline many proteins pathways play essential roles differentiation otic olfactory their integration into non-neuronal support structures. cases, well-known together with region-specific factors transform thickened ectodermal placodes complex sense organs containing numerous, diverse subtypes. Olfactory placodes, combination migratory neural crest stem cells, highly subtypes sound, position movement space, odors pheromones throughout lives.