Infections which cause ileocolic disease in animals: Are they relevant to Crohn's disease?

摘要: There has been a striking rise in incidence of Crohn’s disease the last 20 yr, which is not simply due to increased recognition condition.’ In these circumstances there may be major etiological factor operating environment, and one possibility, considered, an infectious agent. Possible infective agents have identified human studies, although their significance yet established. A variety acute chronic infections affect terminal ileum colon animals, pathology often resembles that seen disease. Animal models received little attention they offer some guide etiology humans. cases extensive efforts made identify causative agent because economic implications food industry. Where such identified, it difficult culture intracellular bacterium. We do suggest conditions animals are disease, but view similarity ileocecal inflammatory bowel humans, would seem pertinent review current literature hope useful areas for investigation. This lead progress with this problem.