NF-kappa B binds within a region required for B-cell-specific expression of major histocompatibility complex class II gene E alpha d.
作者： M A Blanar , L C Burkly , R A Flavell
DOI: 10.1128/MCB.9.2.844
关键词:
摘要: A region upstream of the murine major histocompatibility complex gene, E alpha d, has been shown previously to be required for B-cell expression. Binding of the B-cell-specific factor, NF-kappa B, to a site within this region is indistinguishable from that observed with the kappa enhancer binding site. NF-kappa B may be responsible for E alpha d B-cell expression.
highwire.org参考文章(21)
Laurent Emorine, Michael Kuehl, Lawrence Weir, Philip Leder, Edward E. Max, A conserved sequence in the immunoglobulin J kappa-C kappa intron: possible enhancer element. Nature. ,vol. 304, pp. 447- 449 ,(1983) , 10.1038/304447A0
E.E. Max, J.V. Maizel, P. Leder, The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes. Journal of Biological Chemistry. ,vol. 256, pp. 5116- 5120 ,(1981) , 10.1016/S0021-9258(19)69374-9
Mark M. Garner, Arnold Revzin, A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system Nucleic Acids Research. ,vol. 9, pp. 3047- 3060 ,(1981) , 10.1093/NAR/9.13.3047
Ranjan Sen, David Baltimore, Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism Cell. ,vol. 47, pp. 921- 928 ,(1986) , 10.1016/0092-8674(86)90807-X
Pamela J. Mitchell, Charlotte Wang, Robert Tjian, Positive and negative regulation of transcription in vitro: Enhancer-binding protein AP-2 is inhibited by SV40 T antigen Cell. ,vol. 50, pp. 847- 861 ,(1987) , 10.1016/0092-8674(87)90512-5
J. D. Dignam, R. M. Lebovitz, R. G. Roeder, Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Research. ,vol. 11, pp. 1475- 1489 ,(1983) , 10.1093/NAR/11.5.1475
U Siebenlist, E. coli RNA polymerase interacts homologously with two different promoters Cell. ,vol. 20, pp. 269- 281 ,(1980) , 10.1016/0092-8674(80)90613-3
Kwanyee Leung, Gary J. Nabel, HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor Nature. ,vol. 333, pp. 776- 778 ,(1988) , 10.1038/333776A0
Michael Fried, Donald M. Crothers, Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis Nucleic Acids Research. ,vol. 9, pp. 6505- 6525 ,(1981) , 10.1093/NAR/9.23.6505
R. Flavell, H Allen, L. Burkly, D. Sherman, G. Waneck, G Widera, Molecular biology of the H-2 histocompatibility complex Science. ,vol. 233, pp. 437- 443 ,(1986) , 10.1126/SCIENCE.3726537