Prospective pertussis surveillance in Switzerland, 1991-2006.

摘要: Pertussis has been monitored in Switzerland since 1991 by the nationwide Swiss Sentinel Surveillance Network (SSSN), consisting of approximately 200 general practitioners, internists and pediatricians representing about 3% total primary care physicians these specialities. SSSN members report patients with cough ? 14 days plus either an epidemiological link or characteristic symptoms (paroxysms, whoop, post-tussive vomiting) on a weekly basis to Federal Office Public Health. Confirmatory PCR from nasopharyngeal specimens is offered for free. A 4992 cases have reported until 2006. Yearly incidence dropped 70 per 100,000 inhabitants 1992 40 2006, single epidemic 1994-1995 280-370 cases/100,000. On average 80% were tested PCR, 24% confirmed as Bordetella pertussis infections. For 2.6% complications reported, most commonly pneumonia, asthma bronchiale, otitis media, bronchitis rib fractures. average, 1.5% hospitalized. Disease vaccinated was mitigated less frequent (unvaccinated: 5.1%; 3 doses: 3.0%; 4 1.7%), hospitalizations 3.6%; 1 dose: 1.1%) various clinical compared unvaccinated patients. Comparing periods 1991-1996, 1997-2001 2002-2006, shift age group 1-9 years 10-19 observed among cared practitioners internists. The benefits further booster doses adolescents and/or adults need be considered.