Classic neurothekeoma (nerve sheath myxoma) and cellular neurothekeoma of the oral mucosa: immunohistochemical profiles
作者： Marilena Vered , Eddie Fridman , William M. Carpenter , Amos Buchner
DOI: 10.1111/J.1600-0714.2010.00952.X
关键词:
摘要: J Oral Pathol Med (2011) 40: 174–180 Background: Classic neurothekeoma (nerve sheath myxoma) is regarded as being a true benign cutaneous tumor of nerve origin. Cellular was separated from the classic type by histogenesis, morphology and immunophenotype. Whether cellular represents continuum within spectrum or an independent entity controversial. Only small number neurothekeomas oral mucosa have been reported there are even fewer publications on neurothekeoma. We analyzed series (classic cellular) with panel neural other mesenchymal markers to enhance their diagnosis classification. Methods: One three were submitted immunohistochemical stains antibodies against S100, S100A6, NSE, NKI/C3, PGP9.5, α-SMA, HHF-35, CD68 vimentin. Two cases neurofibroma (plexiform type), representing lesion origin, served control. Results: The yielded positive immunoreaction for S100A6 NKI/C3 negative S-100. demonstrated reaction S-100 but one NKI/C3. Other non-contributory distinguishing between these types lesions. Conclusions: could be due, in part, lack recognition particular morphologic features. Our results indicate that testing immunoreactivity may value
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