From spindle checkpoint to cancer.
作者： Christoph Lengauer , Zhenghe Wang
DOI: 10.1038/NG1104-1144
关键词:
摘要: Truncating and missense mutations in BUB1B, encoding the mitotic spindle checkpoint protein BUBR1, have been identified individuals with mosaic variegated aneuploidy. This finding supports idea that there is a genetic basis for aneuploidy cancers.
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