Pediatric traumatic brain injury: Language outcomes and their relationship to the arcuate fasciculus

摘要: Pediatric traumatic brain injury (TBI) may result in long-lasting language impairments alongside dysarthria, a motor-speech disorder. Whether this co-morbidity is due to the functional links between speech and networks, or widespread damage affecting both motor tracts, remains unknown.Here we investigated function diffusion metrics (using diffusion-weighted tractography) within arcuate fasciculus, uncinate corpus callosum 32 young people after TBI (approximately half with dysarthria) age-matched healthy controls (. n=. 17). Only participants dysarthria showed language, sentence formulation semantic association. In whole group, was best predicted by combined left volumes, suggesting "dual blow" seriously reduces potential for reorganisation. Word comprehension fractional anisotropy right arcuate. The deficits therefore seems be consequence of multiple tract damage. © 2013 Elsevier Inc.