Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells
作者： Jongdae Lee , Ji-Hun Mo , Kyoko Katakura , Irit Alkalay , Adam N. Rucker
DOI: 10.1038/NCB1500
关键词:
摘要: The mechanisms by which commensal bacteria suppress inflammatory signalling in the gut are still unclear. Here, we present a cellular mechanism whereby the polarity of intestinal …
nature.com
unirioja.es
sci-hub.se 参考文章(46)
G.I. Sandle, N. Higgs, P. Crowe, M.N. Marsh, S. Venkatesan, T.J. Peters, Cellular basis for defective electrolyte transport in inflamed human colon Gastroenterology. ,vol. 99, pp. 97- 105 ,(1990) , 10.1016/0016-5085(90)91235-X
A. S. Neish, Prokaryotic Regulation of Epithelial Responses by Inhibition of Ikappa B-alpha Ubiquitination Science. ,vol. 289, pp. 1560- 1563 ,(2000) , 10.1126/SCIENCE.289.5484.1560
K.D. Katz, D. Hollander, C.M. Vadheim, C. McElree, T. Delahunty, V.D. Dadufalza, P. Krugliak, J.I. Rotter, Intestinal permeability in patients with Crohn's disease and their healthy relatives Gastroenterology. ,vol. 97, pp. 927- 931 ,(1989) , 10.1016/0016-5085(89)91499-6
Roel Nusse, Jeremy T Blitzer, A critical role for endocytosis in Wnt signaling ,(2005)
Kazuko Shichijo, Mutsumi Matuu, Yuji Ikeda, Shinji Naito, Masahiro Ito, Ichiro Sekine, Clinicopathologic study of dextran sulfate sodium experimental murine colitis Laboratory Investigation. ,vol. 69, pp. 238- 249 ,(1998) , 10.1016/S0021-5198(19)41298-5
Cesar F. Ortega-Cava, Shunji Ishihara, Mohammad A. K. Rumi, Kousaku Kawashima, Norihisa Ishimura, Hideaki Kazumori, Jun Udagawa, Yasunori Kadowaki, Yoshikazu Kinoshita, Strategic compartmentalization of Toll-like receptor 4 in the mouse gut. Journal of Immunology. ,vol. 170, pp. 3977- 3985 ,(2003) , 10.4049/JIMMUNOL.170.8.3977
S. H. Rhee, E. Im, M. Riegler, E. Kokkotou, M. O'Brien, C. Pothoulakis, Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 102, pp. 13610- 13615 ,(2005) , 10.1073/PNAS.0502174102
B. SCHMAUssER, M. ANDRULIS, S. ENDRICH, S. K. LEE, C. JOSENHANS, H.-K. MULLER-HERMELINK, M. ECK, Expression and subcellular distribution of toll-like receptors TLR4, TLR5 and TLR9 on the gastric epithelium in Helicobacter pylori infection. Clinical and Experimental Immunology. ,vol. 136, pp. 521- 526 ,(2004) , 10.1111/J.1365-2249.2004.02464.X
J. Lee, T.-H. Chuang, V. Redecke, L. She, P. M. Pitha, D. A. Carson, E. Raz, H. B. Cottam, Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7 Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 6646- 6651 ,(2003) , 10.1073/PNAS.0631696100
Elke Cario, Dennis Brown, Mary McKee, Kathryn Lynch-Devaney, Guido Gerken, Daniel K. Podolsky, Commensal-associated molecular patterns induce selective toll-like receptor-trafficking from apical membrane to cytoplasmic compartments in polarized intestinal epithelium. American Journal of Pathology. ,vol. 160, pp. 165- 173 ,(2002) , 10.1016/S0002-9440(10)64360-X