作者: Ana H. Kim , Bruce M. Edwards , Steven A. Telian , Paul R. Kileny , H. Alexander Arts
DOI: 10.1097/00129492-200604000-00014
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摘要: OBJECTIVE To determine whether pre-operative transient otoacoustic emission (TEOAE) patterns are predictive of successful hearing preservation in acoustic neuroma surgery. STUDY DESIGN Retrospective observational study. SETTING Tertiary referral medical center. PATIENTS A convenience sample was identified whom TEOAE data were available patients undergoing surgery from 1993-2004. Ninety-three who met this inclusion criterion. INTERVENTIONS Subjects underwent attempted via middle cranial fossa or retrosigmoid approaches. Routine audiometry, ABR, and TEOAE. MAIN OUTCOME MEASURES Pre- post-operative pure tone speech results categorized into classes A, B, C, D as described the American Academy Otolaryngology guidelines (1995). Hearing defined by maintenance class downgrade to within one post-op. Pre-operative divided five frequency bands positive each band if there a response above noise floor with >50% reproducibility. RESULTS preserved 51 (55%). Of these, 11 (22%) had all measured (1, 1.5, 2, 3, 4 kHz), whereas 40 (78%) responses ranging 0 bands. 42 failed preserve their hearing. only three (7%) bands, 39 (93%) (p<0.05). Other variables prognostic significance our series included smaller tumor size, location IAC, better hearing, shorter latencies on ABR. Logistic regression then used compare value against these variables. In series, ABR 5 showed highest significant correlation CONCLUSION robust pattern may be favorable indicator for potential The enhanced when combined other factors such location, audiometric results.