Role of Ran GTPase in RNA Processing and Export of RNA from the Nucleus to the Cytosol: Insights from Budding Yeast
作者： Anita K. Hopper
DOI: 10.1007/978-1-4615-1501-2_3
关键词:
摘要: The Ran GTPase functions directly in nucleus/cytosol exchange, microtubule and spindle assembly, likely other processes. This chapter focuses on use of the budding yeast (Saccharomyces cerevisiae) model system to delineate vivo roles pathway export tRNAs, ribosomes, mRNA from nucleus cytosol. Emphasis is placed upon complex multiple overlapping pathways that exist possible mechanisms by which cycle may respond environmental cues assure nuclear/cytosol exchange coordinated with cellular metabolism. data support direct for tRNA ribosome nuclear export, but it not clear whether export.
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G. Schlenstedt, D. H. Wong, D. M. Koepp, P. A. Silver, MUTANTS IN A YEAST RAN BINDING PROTEIN ARE DEFECTIVE IN NUCLEAR TRANSPORT The EMBO Journal. ,vol. 14, pp. 5367- 5378 ,(1995) , 10.1002/J.1460-2075.1995.TB00221.X
D.C. Amberg, M. Fleischmann, I. Stagljar, C.N. Cole, M. Aebi, Nuclear PRP20 protein is required for mRNA export. The EMBO Journal. ,vol. 12, pp. 233- 241 ,(1993) , 10.1002/J.1460-2075.1993.TB05649.X
Jeffrey N. Strathern, James R. Broach, Elizabeth W. Jones, The Molecular biology of the yeast Saccharomyces : metabolism and gene expression Cold Spring Harbor Laboratory. ,(1982)
T. Kadowaki, D. Goldfarb, L.M. Spitz, A.M. Tartakoff, M. Ohno, Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily. The EMBO Journal. ,vol. 12, pp. 2929- 2937 ,(1993) , 10.1002/J.1460-2075.1993.TB05955.X
Charles N. Cole, mRNA export: the long and winding road. Nature Cell Biology. ,vol. 2, ,(2000) , 10.1038/35008681
Zhaolan Zhou, Ming-juan Luo, Katja Straesser, Jun Katahira, Ed Hurt, Robin Reed, The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans Nature. ,vol. 407, pp. 401- 405 ,(2000) , 10.1038/35030160
Arie Kaffman, Nicole Miller Rank, Elizabeth M. O'Neill, Linda S. Huang, Erin K. O'Shea, The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus Nature. ,vol. 396, pp. 482- 486 ,(1998) , 10.1038/24898
A. K. Hopper, MOLECULAR BIOLOGY:Nuclear Functions Charge Ahead Science. ,vol. 282, pp. 2003- 2004 ,(1998) , 10.1126/SCIENCE.282.5396.2003
W.C. Shen, D Selvakumar, D.R. Stanford, A.K. Hopper, The Saccharomyces cerevisiae LOS1 gene involved in pre-tRNA splicing encodes a nuclear protein that behaves as a component of the nuclear matrix. Journal of Biological Chemistry. ,vol. 268, pp. 19436- 19444 ,(1993) , 10.1016/S0021-9258(19)36534-2
Kazuko Nishikura, Eddy M. De Robertis, RNA processing in microinjected Xenopus oocytes: Sequential addition of base modifications in a spliced transfer RNA Journal of Molecular Biology. ,vol. 145, pp. 405- 420 ,(1981) , 10.1016/0022-2836(81)90212-6