Novel use of pleural ultrasound can identify malignant entrapped lung prior to effusion drainage

摘要: BACKGROUND The presence of entrapped lung changes the appropriate management malignant pleural effusion from pleurodesis to insertion an indwelling catheter. No methods currently exist identify prior drainage. Our objectives were develop a method using tissue movement and deformation (strain) analysis with ultrasonography compare it existing technique elastance (PEL). METHODS Prior drainage, 81 patients suspected underwent thoracic ultrasound echocardiogram machine. Images atelectatic lower lobe acquired during breath hold, allowing motion strain related cardiac impulse be analyzed mode (M mode) speckle-tracking imaging, respectively. PEL was measured gold-standard diagnosis consensus opinion two interventional pulmonologists according postdrainage imaging. Participants randomly divided into development validation sets. RESULTS Both total significantly reduced in lung. Using data set, area under receiver-operating curves for 0.86 (speckle tracking), 0.79 mode), 0.69 respective cutoffs 6%, 1 mm, 19 cm H 2 O on sensitivity/specificity 71%/85% 50%/85% 40%/100% CONCLUSIONS This novel can which could allow choice definitive (pleurodesis vs catheter), reducing number interventions required treat effusion.