SYSTEMS AND METHODS FOR CHARACTERIZING NUCLEIC ACID IN A BIOLOGICAL SAMPLE

摘要: A cancer detection method includes preparing a library of nucleic acids in biological sample, sequencing the library, preferably with less than 1X coverage, measuring copy number for genes sequenced and comparing measured numbers standard to determine variability or similarity between numbers. Some embodiments include classifying sample as cancer, determining tissue origin and/or stage providing patient diagnosis based on computer system hardware components computer-executable instructions that are executable cause perform steps method.