Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm.
作者： S Aquila , C Guido , A Santoro , P Gazzerro , C Laezza
DOI: 10.1111/J.1476-5381.2009.00570.X
关键词:
摘要: … to modulate sperm lipid metabolism, we first investigated its action on the intracellular content of triglycerides. Our data indicated that rimonabant decreased the triglyceride content in a …
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Kiyoshi Miki, Energy metabolism and sperm function Spermatology. Proceedings of the 10th International Symposium on Spermatology held at El Escorial, Madrid, Spain, 17-22 September 2006. ,vol. 65, pp. 309- 325 ,(2007)
Maurizio Bifulco, Antonietta Santoro, Chiara Laezza, Anna Maria Malfitano, Chapter 7 Cannabinoid Receptor CB1 Antagonists Vitamins and Hormones. ,vol. 81, pp. 159- 189 ,(2009) , 10.1016/S0083-6729(09)81007-8
Visconti Pe, Arcelay E, Sosnik J, Salicioni Am, Allaire A, Wertheimer Ev, Platt, Signalling pathways involved in sperm capacitation. Spermatology. Proceedings of the 10th International Symposium on Spermatology held at El Escorial, Madrid, Spain, 17-22 September 2006.. ,vol. 65, pp. 245- 259 ,(2007)
W.P. KENNEDY, J.M. KAMINSKI, H.H. VAN DER VEN, R.S. JEYENDRAN, D.S. REID, J. BLACKWELL, P. BIELFELD, L.J.D. ZANEVELD, A simple, clinical assay to evaluate the acrosin activity of human spermatozoa. Journal of Andrology. ,vol. 10, pp. 221- 231 ,(1989) , 10.1002/J.1939-4640.1989.TB00092.X
Vincenzo Di Marzo, Sravan K. Goparaju, Lei Wang, Jie Liu, Sándor Bátkai, Zoltán Járai, Filomena Fezza, Grant I. Miura, Richard D. Palmiter, Takayuki Sugiura, George Kunos, Leptin-regulated endocannabinoids are involved in maintaining food intake Nature. ,vol. 410, pp. 822- 825 ,(2001) , 10.1038/35071088
Dolores J. Lamb, World Health Organization Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction, 4th ed. Journal of Andrology. ,vol. 21, pp. 32- 32 ,(2000) , 10.1002/J.1939-4640.2000.TB03272.X
A M Malfitano, C Laezza, S Pisanti, P Gazzerro, M Bifulco, Rimonabant (SR141716) exerts anti‐proliferative and immunomodulatory effects in human peripheral blood mononuclear cells British Journal of Pharmacology. ,vol. 153, pp. 1003- 1010 ,(2008) , 10.1038/SJ.BJP.0707651
C M Gérard, C Mollereau, G Vassart, M Parmentier, Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochemical Journal. ,vol. 279, pp. 129- 134 ,(1991) , 10.1042/BJ2790129
Margaret F. Thomson, G. J. Wishart, Elucidation of the mechanism responsible for the temperature-dependent reversible inactivation of the motility of fowl spermatozoa. British Poultry Science. ,vol. 30, pp. 687- 692 ,(1989) , 10.1080/00071668908417191
Paul Leff, THE TWO-STATE MODEL OF RECEPTOR ACTIVATION Trends in Pharmacological Sciences. ,vol. 16, pp. 89- 97 ,(1995) , 10.1016/S0165-6147(00)88989-0