作者: Russell P. Rother , Camille Bedrosian , Stephen P. Squinto , Leonard Bell
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摘要: The present disclosure relates to, inter alia, compositions containing an inhibitor of human complement and use the in methods for treating or preventing complement-associated disorders. In some embodiments, is chronically administered to patients. a patient amount with frequency maintain systemic inhibition prevent breakthrough. contain antibody, antigen-binding fragment thereof, that binds component C5 protein such as C5a C5b.