Three-year follow-up of patients with bifurcation lesions treated with sirolimus- or everolimus-eluting stents: SEAside and CORpal cooperative study

摘要: Abstract Introduction and objectives To compare the 3-year incidence of major events in patients with bifurcation lesions treated provisional sirolimus-eluting stents vs everolimus-eluting stents. Methods A pooled analysis 2 prospective randomized trials similar methodology (SEAside CORpal) was performed. In these trials, 443 were randomly assigned to treatment either or The clinical follow-up extended up 3 years assess adverse cardiovascular (death acute myocardial infarction target vessel revascularization). Results At years, survival free 93.2% 91.3% stent group ( P = .16). Exploratory land-mark for late (occurring after 12 months) showed significantly fewer group: 1.4% 5.4% .02). Conclusions Provisional stenting is associated low rates at 3-years’ follow-up. results a subanalysis beyond 1 year, showing lower event rate than stents, suggest that studies exploring long-term benefit latest generation drug-eluting are warranted.