Focal mollusciciding: an effective way to augment chemotherapy of schistosomiasis

作者: R.K. Klumpp , K.Y. Chu

DOI: 10.1016/0169-4758(87)90162-1

关键词:

摘要: Fig. 3. Technician spraying niclosamide into a site o f Schistosoma haematobium transmission in the Volta Lake, Ghana The demise of mollusciciding as primary means controlling schistosome endemic areas has been consequence appearance cheap, safe, and effective oral drugs, which have revolutionized control strategies during last 15 years. increase cost molluscicide choice, niclosamide, to over US$18 per kg (70% wettable powder) also factor decline chemical snail control. A third reason failure blanket or area-wide major projects6,14,15. But medical estabkishment may now be placing too much faith use chemotherapy alone schemes health care diminish morbidity schistosomiasis. This optimism grown with increasing availability 'new wonder drug', praziquantel, its continuing reduction price. Similarly, immunologists overly optimistic about prospects for producing delivering an anti-schistosome vaccine near future. balanced approach schistosomiasis should not overlooked. Properly designed preventive measures such improving water supply, sanitation, education, environmental management, though expensive short run, will reduce long-term risks only schistosomiasis,

参考文章(18)
D. Y. Kofi, K. Y. Chu, R. K. Klumpp, Results of three years of cercarial transmission control in the Volta Lake Bulletin of The World Health Organization. ,vol. 59, pp. 549- 554 ,(1981)
J. Duncan, J. D. Christie, F. S. McCullough, Ph. Gayral, Molluscicides in schistosomiasis control Bulletin of The World Health Organization. ,vol. 58, pp. 681- 689 ,(1980)
A. C. Evans, Control of Schistosomiasis in Large Irrigation Schemes by Use of Niclosamide The American Journal of Tropical Medicine and Hygiene. ,vol. 32, pp. 1029- 1039 ,(1983) , 10.4269/AJTMH.1983.32.1029
P. Jordan, Lilian Woodstock, J. A. Cook, Preliminary parasitological results of a pilot mollusciciding campaign to control transmission of Schistosoma mansoni in St Lucia. Bulletin of The World Health Organization. ,vol. 54, pp. 295- 302 ,(1976)
R. K Klumpp, A study of the transmission of Schistosoma haematobium in Volta Lake, Ghana London School of Hygiene & Tropical Medicine. ,(1983) , 10.17037/PUBS.00682402
M.J. Doenhoff, S. Pearson, D.W. Dunne, Q. Bickle, S. Lucas, J. Bain, R. Musallam, O. Hassounah, Immunological control of hepatotoxicity and parasite egg excretion in Schistosoma mansoni infections: stage specificity of the reactivity of immune serum in T-cell deprived mice Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 75, pp. 41- 53 ,(1981) , 10.1016/0035-9203(81)90012-2
G. Barnish, P. Jordan, R.K. Bartholomew, E. Grist, Routine focal mollusciciding after chemotherapy to control Schistosoma mansoni in Cul de Sac valley, Saint Lucia Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 76, pp. 602- 609 ,(1982) , 10.1016/0035-9203(82)90220-6
B. Liese, The Organization of schistosomiasis control programmes Parasitology Today. ,vol. 2, pp. 339- 345 ,(1986) , 10.1016/0169-4758(86)90054-2