Search and treat strategy to eliminate Helicobacter pylori associated ulcer disease

摘要: Peptic ulcer disease is a serious disorder affecting many people and carrying substantial morbidity even mortality as result of bleeding or perforation.1 2 The discovery Helicobacter pylori its main aetiological factor major breakthrough in gastroenterology. We can cure patients that before were suffering from chronic recurrent ailment. After curing the infection, H associated ulcers do not recur, nor complications.3 Quality life improves, use medication diminishes stops, number doctor visits, hospital admissions, absenteeism work decreases. Curing infection may increase expectancy.2 Hence treating only with improved health but also significant economic benefits. It was demonstrated acid suppressants decreases significantly whereas it usually does decrease those non-ulcer dyspepsia.4-7 Some have claimed reflux symptoms and/or oesophagitis develop successfully treated patients. Whether this true development new merely unmasking an already present occult diathesis controversial.8 9 This possible disadvantage outweigh benefits specific patient group. The clinical discoveries regarding are well known to general practitioners, internists, gastroenterologists, microbiologists. Unfortunately, implementation knowledge level actually right remains problematic. In hard change physician behaviour.10Many today still being on demand suppressants, therapy now considered obsolete.11 12 Vreeburg et al showed minority admitted upper gastrointestinal bleed Amsterdam area tested for presence …