PGC-1alpha: turbocharging mitochondria.

Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky, Marc Montminy, PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Nature Medicine. ,vol. 10, pp. 530- 534 ,(2004) , 10.1038/NM1044

Frédéric Picard, Martine Géhin, Jean-Sébastien Annicotte, Stéphane Rocchi, Marie-France Champy, Bert W. O'Malley, Pierre Chambon, Johan Auwerx, SRC-1 and TIF2 Control Energy Balance between White and Brown Adipose Tissues Cell. ,vol. 111, pp. 931- 941 ,(2002) , 10.1016/S0092-8674(02)01169-8

Kitt Falk Petersen, Sylvie Dufour, Douglas Befroy, Rina Garcia, Gerald I Shulman, None, Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes New England Journal of Medicine. ,vol. 350, pp. 664- 671 ,(2004) , 10.1056/NEJMOA031314

Jiandie Lin, Pei-Hsuan Wu, Paul T. Tarr, Katrin S. Lindenberg, Julie St-Pierre, Chen-yu Zhang, Vamsi K. Mootha, Sibylle Jäger, Claudia R. Vianna, Richard M. Reznick, Libin Cui, Monia Manieri, Mi X. Donovan, Zhidan Wu, Marcus P. Cooper, Melina C. Fan, Lindsay M. Rohas, Ann Marie Zavacki, Saverio Cinti, Gerald I. Shulman, Bradford B. Lowell, Dimitri Krainc, Bruce M. Spiegelman, Defects in Adaptive Energy Metabolism with CNS-Linked Hyperactivity in PGC-1α Null Mice Cell. ,vol. 119, pp. 121- 135 ,(2004) , 10.1016/J.CELL.2004.09.013

P. Puigserver, Activation of PPAR Coactivator-1 Through Transcription Factor Docking Science. ,vol. 286, pp. 1368- 1371 ,(1999) , 10.1126/SCIENCE.286.5443.1368

Toshiyuki Araki, YO Sasaki, Jeffrey Milbrandt, Increased Nuclear NAD Biosynthesis and SIRT1 Activation Prevent Axonal Degeneration Science. ,vol. 305, pp. 1010- 1013 ,(2004) , 10.1126/SCIENCE.1098014

Pere Puigserver, Bruce M. Spiegelman, Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator. Endocrine Reviews. ,vol. 24, pp. 78- 90 ,(2003) , 10.1210/ER.2002-0012

Motoaki Sano, Sam C Wang, Manabu Shirai, Fernando Scaglia, Min Xie, Satoshi Sakai, Toru Tanaka, Prathit A Kulkarni, Philip M Barger, Keith A Youker, George E Taffet, Yasuo Hamamori, Lloyd H Michael, William J Craigen, Michael D Schneider, Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure The EMBO Journal. ,vol. 23, pp. 3559- 3569 ,(2004) , 10.1038/SJ.EMBOJ.7600351

Sung Hee Um, Francesca Frigerio, Mitsuhiro Watanabe, Frédéric Picard, Manel Joaquin, Melanie Sticker, Stefano Fumagalli, Peter R. Allegrini, Sara C. Kozma, Johan Auwerx, George Thomas, Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity Nature. ,vol. 431, pp. 200- 205 ,(2004) , 10.1038/NATURE02866

Daniel P Kelly, Richard C Scarpulla, Transcriptional regulatory circuits controlling mitochondrial biogenesis and function Genes & Development. ,vol. 18, pp. 357- 368 ,(2004) , 10.1101/GAD.1177604