Sentinel Node Detection in Malignant Melanoma

摘要: The initial application of intraoperative lymphatic mapping and sentinel lymphadenectomy followed by selective complete (LM/SL/SCLND) was in melanoma. This arose as a solution to the ongoing debate concerning immediate vs. delayed lymph node dissection. Acceptance concept advances nuclear medicine, surgery, pathology aspects procedure have brought it into widespread use for melanoma expanded its other solid tumors that progress through route. Although diagnostic accuracy has been demonstrated multicenter trials, caution should be exercised regarding therapeutic until definitive benefit can shown from well-designed clinical trials. Current issues active discussion are reviewed including ideal nomenclature, significance occult metastatic disease, quality assurance, role LM/SL/SCLND outside high-volume centers.