Methadone dose and post-mortem blood concentration
作者： JOHN R. M. CAPLEHORN , OLAF H. DRUMMER
DOI: 10.1080/0959523021000023171
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摘要: The relationship of methadone dose with post-mortem blood concentration was investigated using data collected from 1994 coronial cases in the Australian state New South Wales. Data on 31 subjects were summarized linear regression. weight-adjusted dose, gender, maintenance treatment status and its interaction adjusted-dose all significant predictors concentration. death a young man toxic effects three daily doses 30 mg are used to give an example pair observed (0.74 mg/l) predicted (0.48 concentrations. estimated for male patients is at least twice trough plasma levels previously published studies living patients. female times level subjects. We conclude that p...
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